Synthesizes 25 years of MSC trials; supports their safety and potential role in engraftment enhancement and immune modulation — a window into future graft engineering.
Updated protocols for pre-HCT evaluation, GVHD prophylaxis, conditioning, and survivorship care. Core framework for quality and accreditation standards.
Recommendations Comprehensive update from EBMT harmonizing transplant indications with modern cellular and gene therapies. Essential reference for transplant program strategy and clinical justification.
Defines the new era of donor choice — prioritizing younger donors, clinical factors, and parallel donor searches rather than rigid HLA hierarchy. A practice-changing guideline for all transplant centers.
